Di-tri-octahedral smectite (generic name) DIGESTION Sold as Bio-Sponge. Digestion and Motility Drugs

Bio-Sponge™, the commercially available Di-Tri-Octahedral smectite product from Platinum Performance Inc., bound 99% of Clostridium difficile toxins A and B and Clostridium perfringens enterotoxins in one in vitro study and effectively neutralized Clostridium toxins in another study.

This product is not intended to diagnose, treat, cure, or prevent any disease. Results - Di-tri-octahedral smectite decreased the amount of each C perfringens exotoxin in co-incubated samples in a dose-dependent manner and was more effective than bismuth subsalicylate at reducing exotoxins in vitro. Di-tri-octahedral smectite has been shown to be effective at absorbing and neutralising endotoxins, particularly those from clostridia, and therefore should be given in any case where there is a potential for either Salmonella or clostridial disease. Di-tri-octahedral smectite effectively adsorbed C perfringens exotoxins in vitro and had a dose-dependent effect on the availability of equine colostral antibodies. Smectite group which includes dioctahedral smectites, such as montmorillonite, nontronite and beidellite, and trioctahedral smectites, such as saponite. In 2013, analytical tests by the Curiosity rover found results consistent with the presence of smectite clay minerals on the planet Mars.

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Di‐tri‐octahedral smectite is a type of clay that adsorbs C. difficile toxins in vitro, 28 and is commonly used in the treatment of CDI in horses. Probiotic therapy has been evaluated in humans with CDI.

Probiotic therapy has been evaluated in humans with CDI. Smectite (Biosponge). Class of drug. Adsorbent, gastrointestinal protectant.

Di-tri-octahedral smectite effectively adsorbed C perfringens exotoxins in vitro and had a dose-dependent effect on the availability of equine colostral antibodies. Results suggested that DTOS may be an appropriate adjunctive treatment in the management of neonatal clostridiosis in horses. In vivo s …

31. Lawler J, Hassel D, Traub- Dargatz Adsorptive effects of di-tri-octahedral smectite on.

As clay moves through the GI tract and colon, it picks up the positively charged substances, and leaves the body through the alimentary canal taking the toxins with it. The aim of this study was to evaluate the effects of a commercially available di-tri-octahedral (DTO) smectite product on clinical signs and prevalence of post-operative diarrhea in horses with colic associated with disease of the large intestine.
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Preliminary studies using a model of lincomycin-induced colitis suggested that di-tri-octahedral (DTO) smectite, a natural clay material, may be useful for the treatment and prevention of colitis in horses ( Herthel, 2000 ).

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2019-08-05

Oral di-tri-octahedral smectite (Biosponge), 500 mg/kg BW, QID was administered for 3 d, and nasoesophageal feeding frequency was reduced. On days 3 and 4 of hospitalization diarrhea was still profuse and watery, and loperamide hydrochloride (Teva Pharmaceuticals USA, Sellerville, Pennsylvania, USA), 0.05 mg/kg BW, QID, PO was added to the treatment plan in an effort to decrease intestinal Comprised of a natural clay, Di-Tri-Octahedral Smectite A negatively charged intestinal adsorbant designed to help support healthy intestinal function Widely used to support healthy gastrointestinal function in foals.Newborn foals: For best results, following an adequate intake of colostrum administer 30cc of Bio-Sponge® Paste 6 hours after the foal first nurses the mare. 2018-04-18 · K-10 di-tri-Octahedral Smectite is not present on state lists from CA, PA, MN, MA, FL, or NJ. California No Significant Risk Level: None of the chemicals in this product are listed . Other Regulations: European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: Not available.

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Article Unit Active component; Bio Sponge platinum: 9500 gr: Di-Tri-Octahedral Smectite: Equi-Sumo AP: 1000 ml: Ricebran oil, Herbs, Gamma-Orizanol: Quietex Paste Syringe

Results - Di-tri-octahedral smectite decreased the amount of each C perfringens exotoxin in co-incubated samples in a dose-dependent manner and was more effective than bismuth subsalicylate at reducing exotoxins in vitro.

Di-tri-octahedral smectite (BiospongeTM) may help absorb luminal intestinal toxins. Nutritional support. Total or partial parenteral (TPN, PPN) nutrition should be considered in neonates.

Sixty-seven horses with surgical disease of the large intestine were randomly assigned to be treated with DTO smectite (n=37; 0.5 kg via nasogastric 2011-01-10 Smectite, a naturally occurring organomineral, has shown promise as a protectant against the overgrowth of pathogenic bacteria by reducing the harmful effects of bacterial toxins. Bio-Sponge™, the commercially available Di-Tri-Octahedral smectite product from Platinum Performance Inc., 2. The composition of claim 1, wherein the smectite is selected from di-tri-octahedral smectite, bentonite, and combinations thereof. 3. The composition of claim 1 comprising a sufficient amount of smectite to treat or prevent Clostridium difficile associated disease, … 2012-08-22 Di-tri-octahedral smectite (BiospongeTM) may help absorb luminal intestinal toxins. Nutritional support. Total or partial parenteral (TPN, PPN) nutrition should be considered in neonates.

(Ca,Na)0.7(Al,Mg,Fe)4-6. A B S T R A C T : A trioctahedral, ferrous smectite has been located in the Di- octahedral.